LEBER HEREDITARY OPTIC NEUROPATHY: DO FOLATE PATHWAY GENE ALTERATIONS INFLUENCE THE EXPRESSION OF MITOCHONDRIAL DNA MUTATION?

Leber Hereditary Optic Neuropathy: Do Folate Pathway Gene Alterations Influence the Expression of Mitochondrial DNA Mutation?

"nBackground: Leber hereditary optic neuropathy (LHON) is an inherited form of bilateral optic atrophy leading to the loss of central vision.  The primary cause of vision loss is mutation in the mitochondrial DNA (mtDNA), however, unknown secon­dary genetic and/or epigenetic risk factors are suggested to influence its neuropat

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Optimization of Third Rail End Elbow Based on NURBS

[Objective] In order to improve the collision performance of the end elbow of the shoe-rail system and enhance the current collection quality, it is necessary to carry out the optimization research on the third-rail end elbow based on NURBS (Non-Uniform Rational B-Spline).[Method] Taking the end elbow gladioli espresso of a certain metro line in Wu

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Focal validation mechanism for Lombok earthquake with image analysis of satellite radar and crust movement GPS observation

Lombok Earthquake on August 5 and August 19, 2018, traces of deformation were analyzed with satellite image data to determine vertical afsm ribbon army deformation in the form of uplift on the ground surface.Earthquake wave analysis provides data on the mechanism at the epicenter in the form of a fault, the major forces axis in the form of the P ax

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Daily medication routine of adolescents with HIV/AIDS

The objective of this study was to describe the sociodemographic, clinical, and behavioral characteristics of the daily medication routine of adolescents with ww1 german helmet decals HIV/AIDS of ages 13 to 19 years, followed at a reference service.This descriptive cross-sectional study was performed with 23 adolescents, using a quantitative approa

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